MSOS Discussion Board

Mannitol - max temp and duration in a warmer

Karen Thompson's picture

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Has anyone seen any guidelines for how long it is OK for mannitol to stay in a warmer? The package insert gives instruction on heating the flexible containers up to 70 degrees C and the flip top vials to 80 degrees C to dissolve crystals, but it does not mention longer term storage in a warmer. Even if you don't have a reference for it, I'd like to know what other folks are doing. Our warmer is set at 106 degrees F, but we are not currently dating the product when we add it to the warmer. Maybe we should be giving it a 14 day expiration like we do for IV fluids. Thanks

BSC vs. Isolator

Gregory A. Poff's picture

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For those institutions compounding sterile Hazardous Drugs, do you utilize a Biological Safety Cabinet (BSC) or a Compounding Aseptic Containment Isolator (CACI) as your Containment Primary Engineering Control (C-PEC)?

What was your rationale in selecting the type ventilated device that you are using?

Use of Phenol for Chemonervation

DiAnthia Patrick's picture

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The pharmacy prepares 5% phenol for OR to use in conjunction with Botox (type A) for neurolysis once weekly. The problem is the stability and sporadic use. I wanted to know if anyone else is doing this procedure using a different product or have recommendations about obtaining phenol with extended stability beyond 7 days please share. Also if your institution has had good success with something else, I'd love for you to share.
This is a children's hospital.

Thanks.

DiAnthia Patrick PharmD
Childrens National Health System

Switch to Levemir

Debbie Vigliotti's picture

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Our Health System is switching from Lantus to Levemir because Lantus price increased by 6800%! In preparing for implementation of the switch, we identified a potential safety issue because the vial of the immediate-acting insulin aspart (Novolog) looks very similar to the vial of the long-acting Levemir (Lantus is a tall and thin vial which helped to differentiate it from the Novolog); both Novolog and Levemir are the same size and shape vial, lettering same font size and color.

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