Hello,
Our institution is evaluating the safety of polysorbate 80 in parenteral medications. While the excipient is used in many products (including foods, lotions, makeup, etc), there are concerns about parenteral administration and the risk for severe hypersensitivity reactions.
The excipient functions as an emulsifier or solubilizing agent and may be required to keep some medications in solution (e.g. docetaxel). For other parenteral medications, inclusion of polysorbate 80 varies by manufacturer.