Hello colleagues,

I am seeking input from other institutions regarding how intraventricular medications (e.g.,alteplase, vancomycin, gentamicin) are prepared at your facility, and whether any additional practices or processes are in place around the delivery of these medication to the end user which may differ from other sterile compound products.

Thank you in advance for your time and collaboration.

Matt

Our institution has previously required a chest x-ray to confirm the line isnt misplaced before administering alteplace for clearance . Our team is considering removing this requirement for a chest x-ray.

Do your institutions require a CXR prior to alteplase administration?

My primary literature search resulted with one finding
https://pubmed.ncbi.nlm.nih.gov/27957798/

Thank you!
Emily Schwabe