surgery

Methadone for perioperative pain management

Thomas Crawford Gwin, III's picture

Forums: 

We have recently had a few of our orthopedists and anesthesiologists inquire about using low dose methadone peri-operatively at doses of 0.1-0.3mg/kg and was curious if any of your facilities had any related experiences you'd care to share. Obviously, with methadone's t1/2 of 12-60 hours, even considering using long-acting opioids for acute pain management gives me significant pause,b ut would also be concerned about QTc effects with increased methadone use. Thoughts?

Methadone for perioperative pain management

Thomas Crawford Gwin, III's picture

Forums: 

We have recently had a few of our orthopedists and anesthesiologists inquire about using low dose methadone peri-operatively at doses of 0.1-0.3mg/kg and was curious if any of your facilities had any related experiences you'd care to share. Obviously, with methadone's t1/2 of 12-60 hours, even considering using long-acting opioids for acute pain management gives me significant pause,b ut would also be concerned about QTc effects with increased methadone use. Thoughts?

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