We’re currently evaluating how to handle the pyridoxine IV shortage at our facility (over 500 beds). Part of our team is considering implementing a hard stop using LMA (an alternative mechanism in EPIC) that would prevent the order from being placed entirely. The intent is to have the provider call the pharmacy directly to discuss the request. This would be a hard stop without an alternative built into the system.

We’re trying to assess if this is the best approach or if there are more effective strategies. I’d love to hear how other facilities are managing this:

Are you using a hard stop or another form of restriction?

Do you have specific criteria or select indications that guide when pyridoxine IV is approved?

Are you offering alternative therapies, or simply restricting use to certain situations?

Any feedback or examples from your institution would be extremely helpful as we work through this. Thank you in advance!