MSOS Discussion Board

USP 797 Relative Humidity Excursion Plan

Ian Campbell's picture

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We have developed and implemented a Relative Humidity Excursion Plan to address humidity concerns >60% in our IV rooms in response to USP 797 (2023). There currently exists no reference on how this should be addressed.

Requesting to see if other institutions have developed a plan and if so, are they willing to share their plan. Ours will be shared as well. Thanks.

Trikafta Question

Emily K. D'Anna's picture

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Hello! Interesting, niche, question from one of our safety-minded outpatient pharmacists regarding the medication Trikafta (elexacaftor, tezacaftor, ivacaftor) for management of CF.

Curious if anyone else has come up with a solution to safely / accurately prescribe and document this medication when dose adjustments are indicated.

This med is supplied as 2 separate products packaged together in a blister card package containing 21 tablets: elexacafter/tezacaftor/ivacaftor (orange capsule-shaped tablet) in fixed-dose combination and ivacaftor (blue capsule-shaped tablets)

Field Action Letter for Exactamix Inlet Tubing

Mara Miller's picture

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Hi,

I wanted to share the attached letter we received from Baxter in case you utilize these affected inlet tubing products and have not yet received the letter.

Regards,
Mara Miller, PharmD BCPS
Medication Safety Coordinator
Kaweah Health Medical Center Pharmacy
400 W Mineral King
Visalia, CA 93291
T: (559) 624-5652

Bivalirudin IV Pump Guardrails

Fiona Lui's picture

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We are re-evaluating our bivalirudin guardrails after a medication error.

Currently we have two library files
Bivalirudin (HIT) & Bivalirudin (PCI), the soft maxes were both set at 1.76 mg/kg/hr and we were planning to lower the bivalirudin (HIT) soft max to 0.6 mg/kg/hr.

Additionally, we were going to rename the (HIT) library file because we are using bivalirudin for indications outside of HIT, like ECMO, but were not coming up with a good alternative name.

Informed Consent for Antineoplastics and Biologics for Non-Onc Indications

Francesca Mernick's picture

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Hello!

We are interested in learning whether your sites require written informed consent for antineoplastics and biologics when used for non-oncology indications in the outpatient infusion setting (i.e. rituximab or infliximab for rheumatoid arthritis).

If yes, do you employ an electronic process for documenting informed consent?

Thank you!
Frankie

Remifentanil PCA for laboring patients

Andrea Rai's picture

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We have an OB patient who has remote spine trauma and was told to avoid spinal/epidural procedures, so one of our anesthesiologists is wanting to do remifentanil PCA for her instead during labor. We have never used remifentanil before so it will be a new build in our EMR software, pump library, etc. The anesthesiologist provided us with a protocol from a facility in Wales as this is apparently common in the UK, but I am unfamiliar with this drug and this is the only protocol I've found so I would like something to compare it to while creating ours.

Definity perflutren reactions

Erin Gavin's picture

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Hi everyone,
I know there is occasionally some talk about Lumason reactions, but wondering if anyone has seen a cluster of severe Definity reactions lately. We had two patients who experienced cardiac arrest almost immediately after administration. Both from Lot 1352/Exp 4/2025. We are reporting to the mfg and MedWatch but interested if this group has seen anything.
Thanks!
Erin

EPIC One Step Meds and Provider Cosignature

Erin Stephanie Radvansky's picture

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Hello. My facility is going to be switching to EPIC soon and one of the decisions that needs to be made is whether or not providers will be required to cosign medications given using EPIC's One Step Medication workflow. I was curious as to what other facilities require and why. Thanks!

Cost savings justification/analysis for Med Safety

Pratixa Patel's picture

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Hello friends,
Would anyone be able to share any literature or any resources that utilizes cost savings or cost justification to support the addition of med safety positions for a healthcare system where the Med Safety Officer (me) has direct oversight of 8 hospitals, 5 free standing Eds, and 6 infusion centers? I am also expected to assist with retail pharmacies and ambulatory clinics. Any information or advice would be greatly appreciated.

Thanks,
Pratixa Patel

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