Dobutamine & Milrinone infusions dosing ranges & titration parameters

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Mon, 06/02/2025 - 15:47
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Fiona Lui
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Dobutamine & Milrinone infusions dosing ranges & titration parameters

Any cardiac centers willing to share their setup/default settings for ordering a titratable dobutamine and/or milrinone here or via fiona.lui@swedish.org

Providers at my institution have proposed that:

-Dobutamine dosing range should be limited 0-10 mcg/kg/min despite Lexicomp's dosing range of 0-20 mcg/kg/min.

-Milrinone dosing range should not exceed 0.375 mcg/kg/min despite Lexicomp's range: 0.125 - 0.75 mcg/kg/minute.

What titration goals do you have available as an option, especially for patients without Pulmonary Artery Catheter?

We have (1) Cardiac index 2 & greater (2) SvO2 60 & greater (3) MAP 65 & greater.
The last (#3) of which is being argued as inappropriate goal for these infusions.

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