Options for heparin resistance in critically ill patients

PLEASE NOTE:   Posts made to this forum should not be considered as the expressed opinions of, nor should be considered endorsed by, the Medication Safety Officer’s Society (MSOS) or the Institute for Safe Medication Practices (ISMP). 

Make sure your email is up-to-date
In order to continue to receive updates from MSOS, as well as forum posts and other valuable information as a member of MSOS, please be sure to update your email address with us, whenever it changes. If you need assistance doing so, please send an email to jgold@ismp.org. 

5 posts / 0 new
Log in or register to post comments
Last post
Mon, 12/18/2017 - 14:57
#1
Leah Cochran
Leah Cochran's picture
Offline
Last seen: 5 months 1 week ago
Joined: 09/30/2013 - 13:18
Options for heparin resistance in critically ill patients

We have recently switched to monitoring heparin assays for our weight based heparin drips and have had several situations where the heparin assays have remained subtherapeutic despite high doses of heparin (>25units/kg/hr). This has been occurring more in our critical care population. Has anyone encountered the same issue and have any guidance on how to manage ( argatroban vs giving thrombin vs alternative monitoring vs other) thanks.

Tags: 

Top